Browsing by Author "Eguibar, Jose R."

Now showing 1 - 3 of 3
  • Artículo
    Follicular development and secretion of ovarian hormones during the juvenile and adult reproductive lives of the myelin mutant taiep rat: an animal model of demyelinating diseases
    (2018-09-16) Muñoz de la Torre, Luz Patricia; Eguibar, Jose R.; Cortes, Carmen; Ugarte, Araceli; Trujillo Hernández, Angélica; Muñoz de la Torre, Luz Patricia; 0000-0003-2176-0239; Eguibar, Jose R; 0000-0001-6594-1141; Cortes, Carmen; 0000-0002-9163-2665; Ugarte, Araceli; 0000-0001-6020-3780; Trujillo Hernández, Angélica; 0000-0002-9931-9294
    "Infertility and reproductive problems have been reported in women with several neurological disorders, for example, demyelination. However, the physiology of such problems has remained unknown so far. The taiep rats are an animal neurological model that initially shows a hypomyelination followed by a progressive demyelination of the central nervous system. This animal has reproductive problems, and the aim of this work is to characterize the follicular development, secretion of ovarian hormones, and presence of noradrenaline in the ovaries of the female taiep rats in the juvenile and adult stages. The taiep rats have low body weight (approximately 19% less than that of SD rats), a delay of 4 days in the age of vaginal opening, and an irregularity in the estrous cycle by the absence or prolongation of some estral cycle stage. In the juvenile stage, we observed a decrease of approximately 44% in the total number of follicles with a 15% increase of atresia and an 80% decrease in the fluorescence intensity of catecholamines in the ovaries, with a 21% increment in plasma concentrations of testosterone".
  • Artículo
    Mating-induced analgesia is dependent of copulatory male pattern in high- and low- yawning male rats
    (2022-03-15) Gómora Arrati, Porfirio; Cortes, Carmen; Trujillo Hernández, Angélica; Encarnación Sánchez, José L.; Galicia Aguas, Yadira L.; González Flores, Oscar; Eguibar, Jose R.; Trujillo Hernández, Angélica; 0000-0002-9931-9294; Eguibar, Jose R; 0000-0001-6594-1141
    "Mating behavior in rodents can modulate pain sensations in both sexes. In males, the execution of mounts, intromissions, and ejaculations induced a progressive increase in their vocalization thresholds induced by tail shocks and other types of noxious stimuli. We selectively inbred two sublines from Sprague-Dawley (SD) rats that differed in their spontaneous yawning frequency. The high-yawning (HY) subline had a mean of 20 yawns/h and a different pattern of sexual behavior characterized by longer interintromission intervals and more sexual bouts that delayed ejaculation. The low-yawning (LY) subline and SD rats yawned as a mean 2 and 1 yawns/h, respectively. So, we determine mating-induced analgesia in HY, LY, and SD male rats by measuring vocalization thresholds in response to noxious electric tail shocks. Our results showed that the magnitude of mating-induced analgesia was lower in HY and LY rats with respect to SD rats. When the rats performed different components of male sexual pattern, both sublines exhibited a significantly lower increase in their vocalization thresholds with respect to SD rats—being sublines less responsive regarding mating-induced analgesia".
  • Artículo
    Yawning and penile erection frequencies are resilient to maternal care manipulation in the high-yawning subline of Sprague–Dawley rats
    (2020-03-12) Dorantes Nieto, Ángeles; Cortes, Carmen; Ugarte, Araceli; Trujillo Hernández, Angélica; Carrasco, Ángeles; Cepeda Freyre, Héctor Alejandro; Eguibar, Jose R.; Ugarte, Araceli; 0000-0001-6020-3780; Trujillo Hernández, Angélica; 0000-0002-9931-9294; Eguibar, Jose R; 0000-0001-6594-1141
    "Yawning is a stereotyped behavioral pattern characterized by wide opening of the mouth associated with deep inspiration followed by short expiration. All vertebrate species yawn, but with low frequencies. We obtained two sublines of Sprague–Dawley (SD) rats by a strict inbreeding process: one with a high-yawning frequency (HY) of 20 yawns/h, which is one order of magnitude higher with respect to the low-yawning frequency (LY) subline, with 2 yawns/h. Outbred SD rats had a yawning frequency of 1 yawn/h. HY dams had a different organization of maternal care with respect to that displayed by LY and SD dams because HY dams constructed lower quality nests and had more re-retrieving and atypical retrieving. The aim of this study was to analyze the changes in maternal care using in- and cross-fostering between the sublines and SD dams and to measure spontaneous and dopaminergic-induced yawning, penile erections, grooming and scratching bouts. We also measured the expression of dopamine D2 receptors in the striatum using Western blot analysis".