Browsing by Author "Rosas, Gabriela"

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  • Artículo
    The neural signals of the superior ovarian nerve modulate in an asymmetric way the ovarian steroidogenic response to the vasoactive intestinal peptide
    (2018-08-20) Rosas, Gabriela; Linares, Rosa; Ramírez, Deyra A.; Vieyra Valdez, Elizabeth; Trujillo Hernández, Angélica; Domínguez, Roberto; Morales Ledesma, Leticia; Linares, Rosa; 0000-0002-5575-4120; Vieyra Valdez, Elizabeth; 0000-0001-9413-4808; Trujillo Hernández, Angélica; 0000-0002-9931-9294; Morales Ledesma, Leticia; 0000-0002-5276-8260
    "The superior ovarian nerve (SON) provides neuropeptide-Y, norepinephrine and vasoactive intestinal peptide (VIP) to the ovaries. Ovarian steroidogenesis is modulated by the SON. In the cyclic rat, the acute steroidogenic response to ovarian microinjection of VIP is asymmetric and varies during the estrous cycle. In the present study, we analyze whether the differential effects of VIP in each ovary are modulated by the neural signals arriving through the SON. Cyclic female rats were submitted on diestrus-1, diestrus-2, proestrus, or estrus to a unilateral section of the SON, and immediately afterward, the denervated ovary was either microinjected or not with VIP. Animals were sacrificed 1 h after treatment. The injection of VIP into the left denervated ovary performed on diestrus-1 decreased progesterone levels in comparison with the left SON sectioning group; similar effects were observed on proestrus when VIP was injected into either of the denervated ovaries".