Browsing by Author "Ugarte Duarte, Araceli"

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  • Artículo
    Follicular development and secretion of ovarian hormones during the juvenile and adult reproductive lives of the myelin mutant taiep rat: an animal model of demyelinating diseases
    (2018-09-16) Cortes Sánchez, Ma. del Carmen; Eguibar Cuenca, José Ramon; Muñoz de la Torre, Luz Patricia; Ugarte Duarte, Araceli; Trujillo Hernández, Angélica; Cortes Sánchez, Ma. del Carmen; 0000-0002-9163-2665; Eguibar Cuenca, José Ramon, 0000-0001-6594-1141; Muñoz de la Torre, Luz Patricia; 0000-0003-2176-0239; Ugarte Duarte, Araceli; 0000-0001-6020-3780; Trujillo Hernández, Angélica; 0000-0002-9931-9294
    "Infertility and reproductive problems have been reported in women with several neurological disorders, for example, demyelination. However, the physiology of such problems has remained unknown so far. The taiep rats are an animal neurological model that initially shows a hypomyelination followed by a progressive demyelination of the central nervous system. This animal has reproductive problems, and the aim of this work is to characterize the follicular development, secretion of ovarian hormones, and presence of noradrenaline in the ovaries of the female taiep rats in the juvenile and adult stages. The taiep rats have low body weight, a delay of 4 days in the age of vaginal opening, and an irregularity in the estrous cycle by the absence or prolongation of some estral cycle stage. The demyelination in taiep rats affects follicular development and steroidogenesis in the early stages of the animal’s life, and this is maintained util adulthood".