Follicular development and secretion of ovarian hormones during the juvenile and adult reproductive lives of the myelin mutant taiep rat: an animal model of demyelinating diseases

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dc.audiencegeneralPublices_MX
dc.contributor.authorMuñoz de la Torre, Luz Patricia
dc.contributor.authorEguibar, Jose R.
dc.contributor.authorCortes, Carmen
dc.contributor.authorUgarte, Araceli
dc.contributor.authorTrujillo Hernández, Angélica
dc.creatorMuñoz de la Torre, Luz Patricia; 0000-0003-2176-0239
dc.creatorEguibar, Jose R; 0000-0001-6594-1141
dc.creatorCortes, Carmen; 0000-0002-9163-2665
dc.creatorUgarte, Araceli; 0000-0001-6020-3780
dc.creatorTrujillo Hernández, Angélica; 0000-0002-9931-9294
dc.date.accessioned2023-02-03T18:17:44Z
dc.date.available2023-02-03T18:17:44Z
dc.date.issued2018-09-16
dc.description.abstract"Infertility and reproductive problems have been reported in women with several neurological disorders, for example, demyelination. However, the physiology of such problems has remained unknown so far. The taiep rats are an animal neurological model that initially shows a hypomyelination followed by a progressive demyelination of the central nervous system. This animal has reproductive problems, and the aim of this work is to characterize the follicular development, secretion of ovarian hormones, and presence of noradrenaline in the ovaries of the female taiep rats in the juvenile and adult stages. The taiep rats have low body weight (approximately 19% less than that of SD rats), a delay of 4 days in the age of vaginal opening, and an irregularity in the estrous cycle by the absence or prolongation of some estral cycle stage. In the juvenile stage, we observed a decrease of approximately 44% in the total number of follicles with a 15% increase of atresia and an 80% decrease in the fluorescence intensity of catecholamines in the ovaries, with a 21% increment in plasma concentrations of testosterone".es_MX
dc.identifierhttps://doi.org/10.1155/2018/5718782
dc.identifier.urihttps://hdl.handle.net/20.500.12371/17343
dc.language.isoenges_MX
dc.rights.accesopenAccesses_MX
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0es_MX
dc.titleFollicular development and secretion of ovarian hormones during the juvenile and adult reproductive lives of the myelin mutant taiep rat: an animal model of demyelinating diseaseses_MX
dc.typeArtículoes_MX
dc.type.conacytarticlees_MX
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