Obese female Zucker rats (fa/fa) exhibit dendritic retraction in neurons in the ventromedial hypothalamic nucleus

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dc.audiencegeneralPublices_MX
dc.contributor.authorBravo Durán, Dolores Adriana
dc.contributor.authorBarreda Guzmán, Selina Jocelyn
dc.contributor.authorTrujillo Hernández, Angélica
dc.contributor.authorSilva Gómez, Adriana Berenice
dc.creatorTrujillo Hernández, Angélica; 0000-0002-9931-9294
dc.creatorSilva Gómez, Adriana Berenice; 0000-0002-0434-9168
dc.date.accessioned2023-02-03T17:29:45Z
dc.date.available2023-02-03T17:29:45Z
dc.date.issued2021-04
dc.description.abstract"The ventromedial hypothalamic nucleus (VMH) is located in the tuberal region of the hypothalamus and is traditionally considered the satiety center. In obese Zucker rats, which express a mutation in the leptin receptor gene and exhibit obesity from the first weeks of life, the morphology of VMH neurons is unknown. In the present study, we found that the dendritic length of VMH neurons in obese Zucker rats was significantly shorter than that in Long Evans rats. This finding allows us to suggest that obese Zucker rats exhibit both neuronal metabolic alterations related to leptin and a reduction in the flow of information within the neuronal circuits in which the VMH nucleus participates to regulate foraging".es_MX
dc.identifierhttps://doi.org/10.1016/j.jchemneu.2021.101919
dc.identifier.urihttps://hdl.handle.net/20.500.12371/17339
dc.language.isoenges_MX
dc.rights.accesopenAccesses_MX
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0es_MX
dc.subject.otherZucker ratses_MX
dc.subject.otherVentromedial hypothalamic nucleuses_MX
dc.subject.otherVentromedial hypothalamic nucleuses_MX
dc.subject.otherDendritic lengthes_MX
dc.subject.otherDendritic retractiones_MX
dc.titleObese female Zucker rats (fa/fa) exhibit dendritic retraction in neurons in the ventromedial hypothalamic nucleuses_MX
dc.typeArtículoes_MX
dc.type.conacytarticlees_MX
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