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Browsing by Author "Arroyo Carmona, Rosa Elena"
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Artículo Heart rate variability as early biomarker for the evaluation of diabetes mellitus progress(2016-04-14) Arroyo Carmona, Rosa Elena; López Serrano, Ana Laura; Albarado Ibañez, Alondra; Mendoza Lucero, Francisca María Fabiola; Medel Cajica, David; López Mayorga, Ruth Mery; Torres Jácome, Julián; Arroyo Carmona, Rosa Elena; 0000-0002-0471-994X; Albarado Ibañez, Alondra; 0000-0002-4725-7714; Mendoza Lucero, Francisca María Fabiola; 0000-0001-6368-265X"According to the American Diabetes Association (ADA), the side effects of diabetes mellitus have recently increased the global health expenditure each year. Of these, the early diagnostic can contribute to the decrease on renal, cardiovascular, and nervous systems complications. However, the diagnostic criteria, which are commonly used, do not suggest the diabetes progress in the patient. In this study, the streptozotocin model in mice (cDM) was used as early diagnostic criterion to reduce the side effects related to the illness. The results showed some clinical signs similarly to five-year diabetes progress without renal injury, neuropathies, and cardiac neuropathy autonomic in the cDM-model. On the other hand, the electrocardiogram was used to determine alterations in heart rate and heart rate variability (HRV), using the Poincaré plot to quantify the HRV decrease in the cDM-model. Additionally, the SD1/SD2 ratio and ventricular arrhythmias showed increase without side effects of diabetes. Therefore, the use of HRV as an early biomarker contributes to evaluating diabetes mellitus complications from the diagnostic".Artículo The role of the autonomic nervous system on cardiac rhythm during the evolution of diabetes mellitus using heart rate variability as a biomarker(2019-05-09) Albarado Ibañez, Alondra; Arroyo Carmona, Rosa Elena; Sánchez Hernández, Rommel; Ramos Ortiz, Geovanni; Frank, Alejandro; García Gudiño, David; Torres Jácome, Julián; Albarado Ibañez, Alondra; 0000-0002-4725-7714; Arroyo Carmona, Rosa Elena; 0000-0002-0471-994X; Sánchez Hernández, Rommel; 0000-0002-4008-4179"Heart rate variability (HRV) is highly influenced by the Autonomic Nervous System (ANS). Several illnesses have been associated with changes in the ANS, thus altering the pattern of HRV. However, the variability of the heart rhythm is originated within the Sinus Atrial Node (SAN) which has its own variability. Still, although both oscillators produce HRV, the influence of the SAN on HRV has not yet been exhaustively studied. On the other hand, the complications of diabetes mellitus (DM), for instance, nephropathy, retinopathy, and neuropathy, increase cardiovascular morbidity and mortality. Traditionally, these complications are diagnosed only when the patient is already suffering from the negative symptoms these complications implicate. Consequently, it is of paramount importance to develop new techniques for early diagnosis prior to any deterioration on healthy patients. HRV has been proved to be a valuable, noninvasive clinical evidence for evaluating diseases and even for describing aging and behavior. In this study, several ECGs were recorded and their RR and PP intervals were analyzed to detect the interpotential interval (ii) of the SAN. Additionally, HRV reduction was quantified to identify alterations in the nervous system within the nodal tissue via measuring the SD1/SD2 ratio in a Poincaré plot".